FIELD: medicine, steroids, pharmacy. SUBSTANCE: invention relates to the use of α-fluoro-25-hydroxy-16-ene-23-incholecalciferol as an agent used for treatment of sebaceous gland sickness, for example, acne rash or seborrheic dermatitis. An agent can be obtained by removal of protecting groups from the corresponding compound containing the protective hydroxylsilyl-groups. Invention proposes also a pharmaceutical composition based on thereof. EFFECT: enhanced effectiveness of an agent. 6 cl, 3 tbl
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