COMPOSITION FOR STIMULATION AND ENHANCEMENT OF PRODUCTION OF ANTIBODY THAT RECOGNIZE GANGLIOSIDE Russian patent published in 2001 - IPC

Abstract RU 2174013 C2

FIELD: medicine, immunology. SUBSTANCE: invention proposes the composition for stimulation or enhancement of production of antibodies that are able to recognize ganglioside in person to whom composition is administrated. Composition has some amount of ganglioside (or its oligosaccharide moiety) conjugated with immunogenic protein and this amount is effective to stimulate or enhance production of antibodies in person. Composition has also adjuvant and pharmaceutically acceptable carrier. Invention proposes also method of use of composition for treatment or prophylaxis of cancer when gangliosides are located on surface or in stroma of cancer cells. EFFECT: enhanced effectiveness of composition. 34 cl, 14 tbl, 26 dwg

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RU 2 174 013 C2

Authors

Filip O. Livingston

Fridkhehl'M Khelling

Dates

2001-09-27—Published

1994-01-21—Filed