FIELD: chemistry.
SUBSTANCE: invention relates to a compound used in medicine, said compound having the formula
,
where n – an integer from 1 to 1,500, m is an integer from 1 to 10, each of the units Globo H (Fucα1→2 Galβ1→3 GalNAcβ 1→3 Galα1→4 Galβ1→4 Glc) covalently bonded to the keyhole limpet hemocyanin (KLH) subunit through residues of basic amino acids selected from arginine, lysine, histidine, and combinations thereof, through the depicted linker, wherein the ratio of epitopes to carrier molecules is in the range of 750 to 3,000.
EFFECT: new compounds have been proposed, as well as pharmaceutical compositions based on said compounds, which are effective in the treatment of cancer and the production of monoclonal antibodies for therapeutic or diagnostic purposes.
45 cl, 5 tbl, 8 ex, 33 dwg
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Authors
Dates
2018-09-06—Published
2014-09-15—Filed