FIELD: biotechnology, microbiology. SUBSTANCE: method involves preparing Escherichia coli biomass and addition of sterile natural sap of higher edible fungus Shii-take as a stimulating agent taken in volume 2% of protective medium volume followed by package in ampoules and drying by lyophilization. Preparation shows the enhanced regenerative capacity of intestine bacillus. EFFECT: enhanced therapeutic effect of preparation. 1 tbl
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