LIPOSOME COMPOSITION OF HUMAN CALCITONIN GENE PEPTIDE AND METHOD OF ITS PREPARING Russian patent published in 2001 - IPC

Abstract RU 2174843 C2

FIELD: medicine, pharmacy. SUBSTANCE: pharmaceutical composition of human calcitonin gene peptide has liposomes made of natural soybean phospholipid in the weight ratio of human calcitonin gene peptide to phospholipid = (1-2):(100-8000). Half-life value for composition is above 72 h. Composition can be administrated by intravenous route, by mucusa mouth and nose spraying in the dose 0.1-10 pg of human calcitonin gene peptide/kg of body mass for treatment of patients with hypertension and congested cardiac insufficiency. Biological availability of composition is about 80%. Invention provides effective prophylaxis and treatment of cardiovascular diseases. EFFECT: enhanced effectiveness, prolonged stability of composition. 8 cl, 8 tbl, 3 ex

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RU 2 174 843 C2

Authors

Vo Veikhan

Dates

2001-10-20Published

1997-11-28Filed