FIELD: medicine, pharmacy. SUBSTANCE: pharmaceutical composition of human calcitonin gene peptide has liposomes made of natural soybean phospholipid in the weight ratio of human calcitonin gene peptide to phospholipid = (1-2):(100-8000). Half-life value for composition is above 72 h. Composition can be administrated by intravenous route, by mucusa mouth and nose spraying in the dose 0.1-10 pg of human calcitonin gene peptide/kg of body mass for treatment of patients with hypertension and congested cardiac insufficiency. Biological availability of composition is about 80%. Invention provides effective prophylaxis and treatment of cardiovascular diseases. EFFECT: enhanced effectiveness, prolonged stability of composition. 8 cl, 8 tbl, 3 ex
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Authors
Dates
2001-10-20—Published
1997-11-28—Filed