COMBINATION OF INHIBITORS OF NO-SYNTHETASE AND SCAVENGERS OF OXYGEN REACTIVE SPECIES Russian patent published in 2001 - IPC

FIELD: medicine, biochemistry, pharmacy. SUBSTANCE: invention claims the novel pharmaceutical preparation used for treatment of patients with pathological states induced by particification of nitrogen monooxide and reactive species of oxygen. Pharmaceutical preparation has at least one substance inhibiting activity of NO-synthetase and at least one substance scavenging reactive species of oxygen. Invention claims also other variant of the preparation made as separate forms for simultaneous or successive use. One of the form has at least one substance inhibiting activity of NO- synthetase and the other form has at least one substance scavenging reactive species of oxygen. Compounds of pharmaceutical preparations act synergetically. EFFECT: decreased doses of active substances, diminished symptoms of unfavorable adverse effects. 15 cl, 5 tbl, 3 ex