DERIVATIVES OF L-ARGININE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION INHIBITING ACTIVITY OF NO-SYNTHASE Russian patent published in 2001 - IPC

FIELD: biochemistry, amino acids. SUBSTANCE: invention describes compounds of the formula (I) and their pharmaceutically acceptable salts where substituents have values indicated in the description. Invention describes also to method of synthesis of compound of the formula (I) and pharmaceutical composition containing effective amount of compound of the formula (I) as an active component and pharmaceutically acceptable carrier or vehicle. The end compounds act as biological inhibitors of NO-synthase and they are useful as hypotensive, antibacterial, immunosuppressive, antiatherosclerotic, vasotrophic, analgetic, antimigraine, ophthalmological or antidiabetic preparations. EFFECT: improved method of synthesis and preparing, valuable medicinal properties. 11 cl, 5 tbl