2-OXOBUTANOIC ACIDS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2001 - IPC

Abstract RU 2175966 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to novel derivatives of 4-oxobutanoic acid of the formula (I) where groups A and B are taken independently each of other among mono- or bicyclic aryl group taken among phenyl and naphthyl, cycloalkyl-group with from 5 to 8 carbon atoms, saturated heterocyclic group taken among tetrahydrofuryl-group. Groups A and B can have from 1 to 3 substitutes taken among C1- C6-alkyl group, C1- C6-alkoxy-group, halogen atom or two substitutes in common mean methylenedioxy- -group. Invention relates to also a pharmaceutical composition containing the compound of the formula (I) as an active component. The proposed new derivatives of 4-oxobutanoic acid can be used for treatment of patients with diabetes mellitus. EFFECT: new compounds indicated above, valuable medicinal properties. 4 cl, 3 tbl

Similar patents RU2175966C2

Title Year Author Number
α-(1-PIPERAZINYL)-ACETAMIDO-DERIVATIVES OF ARENE CARBOXYLIC ACID, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT 1998
  • Muane Zherar
  • Botton Zherar
  • Patero Zherar
  • Doar Lilian
  • Kergoa Mishelin
  • Mesanzho Did'E
  • Bajerer Donal'D D.
RU2198881C2
TRIAZEPINONES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION 1999
  • Rugg'Ero Dan'El'
  • V'Ernsperger Nikola
  • Patero Zherar
  • Muane Zherar
RU2197483C2
DERIVATIVES OF 4-(1-PIPERAZINYL)-BENZOIC ACID, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION 1997
  • Muane Zherar
  • Botton Zherar
  • Doare Lilian
  • Kergoa Mishlin
  • Messanzhu Did'E
RU2178786C2
DERIVATIVES OF PIPERIDINYLMETHYLOXAZOLIDINE-2-ONE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1996
  • Khel'Mut Prjukher
  • Gerd Bartoshik
RU2175970C2
PIPERAZINE DERIVATIVES, METHOD FOR THEIR PREPARING AND COMPOSITION COMPRISING THEREOF 1999
  • Muane Zherar
  • Maria Dominik
  • Mesanzhu Did'E
  • Duare Lil'Jana
  • Kergoa Mishlina
RU2208610C2
PIPERAZINE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION 1997
  • Arl'T Mikhael'
  • Bettkher Khenning
  • Bartoshchik Gerd
  • Zejfrid Kristof
RU2180660C2
[(AMINOIMINOMETHYL)AMINO]ALKANECARBOXIDAMIDES AND THEIR APPLICATION IN THERAPY 1999
  • Mone Zherar
  • Kravo Dan'El'
  • Mesanzho Did'E
  • Doare Lil'Jana
  • Kergoa Mishlina
RU2236401C2
4-ARYLOXY- OR 4-ARYLTHIOPIPERIDINE DERIVATIVES, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION CONTAINING ON SAID AND METHOD OF ITS PREPARING 1994
  • Khel'Mut Prjukher
  • Rudol'F Gottshlikh
  • Gerd Bartoshik
  • Kristof Zejfrid
RU2135495C1
5-PHENOXYALKYL-2,4-THIAZOLIDINEDIONES, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND INTERMEDIATE COMPOUNDS 1997
  • Muane Zherar
  • Botton Zherar
  • Prjun'Jar Eht'En
  • Doar Lilian
  • Kergoa Mishelin
  • Mezanzho Did'E
RU2169144C2
COMPOUNDS CONTAINING ORGANOFLUOROCHLOROPHOSPHATE ANIONS 2007
  • Ignat'Ev Nikolaj
  • Bisski German
  • Vill'Ner Khel'Ge
RU2465278C2

RU 2 175 966 C2

Authors

Muane Zherar

Doar Lilian

Kergoa Mishelin

Mezeraj Filipp

Mezanzho Did'E

Dates

2001-11-20Published

1997-08-05Filed