SCREENING ANALYSIS OF COMPOUNDS STIMULATING PRODUCTION OF SOMATOSTATIN AND INSULIN Russian patent published in 2002 - IPC

Abstract RU 2178714 C2

FIELD: medicine, endocrinology. SUBSTANCE: invention relates to method of construction of compounds that mimic effect of Pbx in stabilizing binding factor-1 in transcription process of somatostatin (STF-1). Using the known analysis data of DNA binding specialist in this field is able to screen compounds in order to determine medicinal agents eliciting the effectiveness in promoting STF-1 binding with DNA. By this way it is possible to discover novel compound that are useful in stimulation of somatostatin and insulin producing. EFFECT: broadened arsenal of methods of screening analysis of compounds useful for normalization of endocrine system function. 6 cl, 21 dwg

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RU 2 178 714 C2

Authors

Montmini Mark R.

Pirs Bernard

Dates

2002-01-27—Published

1996-11-27—Filed