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2 179 981

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IPC

(21) (22)

Application

99109975/04, 1997-10-15

(24)

Start date

1997-10-15

(22)

Actual filing date

1997-10-15

(45)

Published

2002-02-27

(72)

Inventor

Matsumoto AkiesiVaki Mitinori

(73)

Holder

Sejkagaku Korporejshn

TRANSIENT METAL SALTS WITH POLYPEPTIDE AND METHOD OF ENHANCEMENT OF POLYPEPTIDE ACTIVITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS (HIV) Russian patent published in 2002 - IPC

Abstract RU 2179981 C2

FIELD: organic chemistry, polypeptide salts, virology. SUBSTANCE: invention relates to compounds of polypeptide salt of the formula (I) where A1, A2, A3, A4, X, Y and Z have values given in the invention claim and transient metal that show high antiviral activity against human immunodeficiency virus. Invention describes also method of enhancement of activity of polypeptide compound of the formula (I) against HIV that involves conversion of indicated polypeptide to the transient metal salt. Invention describes also the pharmaceutical composition containing the compound of polypeptide salt (I) with transient metal and eliciting antiviral activity. EFFECT: enhanced anti- HIV activity of polypeptide. 7 cl, 2 tbl, 3 ex

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RU 2 179 981 C2

Authors

Matsumoto Akiesi

Vaki Mitinori

Dates

2002-02-27—Published

1997-10-15—Filed

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