FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to novel derivatives of oxadiazole of the general formula (I) 
where X and Y mean oxygen or nitrogen atom being X and Y can not be oxygen or nitrogen simultaneously; Z means radical of the formula (II) 
; 
means phenyl radical that can be substituted directly or through alkylene bridges with number of carbon atoms from 1 to 4 by two- fold or threefold with one or some substituents taken among the order: halogen atom, R1-alkyl, C1-C4. Derivatives of oxadiazole of the general formula (I) can be used as drugs in neurodegenerative diseases and brain ischemia of different genesis: epilepsy, CF3-NR5R6,NO2,-OR7, hypoxia, anoxia, brain trauma, brain edema, amyotropic lateral sclerosis, Huntington chorea, Alzheimers's disease. EFFECT: new compounds indicated above, valuable medicinal properties. 8 cl, 6 tbl, 10 ex _
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