FIELD: organic chemistry, purines. SUBSTANCE: invention relates to new derivatives of xanthine of the formula (I) 
where values R1,R2,R3,R4 are given in p. 1 of the invention claim. Derivatives show antagonistic properties with respect to adenosine. EFFECT: new xanthine derivatives, antagonism to adenosine. 6 cl, 2 tbl, 24 ex
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