FIELD: chemistry of peptides. SUBSTANCE: invention relates to novel peptides of the general formula (I): H-a-Lys-b-Trp- Lys-c-Pro-d-Lys-Pro-Trp-e-Arg-NH2 where a means Ile- or Lys-; b means Pro- or Lys-; c, d mean - Lys- or Trp-; e means Arg or Ala showing biocide activity. Peptides combine the enhanced activity as compared with indolicidine and do not show damage effect on blood cells. EFFECT: new peptides indicated above, enhanced activity. 1 cl, 4 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DECAPEPTIDE SHOWING ANTITUMOR ACTIVITY | 1993 |
|
RU2084458C1 |
| BIOCIDAL PEPTIDE AND THE PREPARATION ON ITS BASIS | 2017 |
|
RU2678985C2 |
| NEW POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION AGAINST HIV-INFECTION | 1994 |
|
RU2136696C1 |
| PROTECTED DERIVATIVES OF VASOPRESSIN | 1997 |
|
RU2123498C1 |
| MODIFIED LIPIDATED RELAXIN B-CHAIN PEPTIDES AND THEIR THERAPEUTIC USE | 2019 |
|
RU2804702C2 |
| PEPTIDE OR ITS ORGANIC OR INORGANIC SALTS, METHOD OF SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHODS OF GROWTH HORMONE RELEASE STIMULATION AND ITS BLOOD CONTENT INCREASE | 1992 |
|
RU2126014C1 |
| METHOD OF TREATING ACUTE PERIODONTITIS | 2018 |
|
RU2684290C1 |
| PEPTIDE STIMULATING NEUTROPHYLE MIGRATION | 2000 |
|
RU2181728C1 |
| SUBSTITUTED BISDIPEPTIDE WITH NEUROPROTECTIVE AND ANTIDEPRESSANT EFFECT | 2014 |
|
RU2559880C1 |
| CYCLIC PEPTIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL COMPOSITION | 1992 |
|
RU2096415C1 |
