INHIBITORS OF PRENYLTRANSFERASES Russian patent published in 2002 - IPC

Abstract RU 2186776 C2

FIELD: organic chemistry, biochemistry, enzymes. SUBSTANCE: invention relates to compounds of the formulas (I) and (II) with values of radicals R1-R18 described in description that show ability to inhibit activity of prenyltransferases. Compounds are effective inhibitors of tumor cells proliferation also. Invention describes also dimeric compounds comprising residues of compounds of the formulas (I) and (II) and a method of treatment of tumors or restenosis in patient that involves administration of these compounds to patient. EFFECT: valuable medicinal properties of compounds. 17 cl

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RU 2 186 776 C2

Authors

Dong Zheng Ksin

Kim Sun Kh.

Dates

2002-08-10Published

1997-05-06Filed