FIELD: organic chemistry, biochemistry, enzymes. SUBSTANCE: invention relates to compounds of the formulas (I) and (II) with values of radicals R1-R18 described in description that show ability to inhibit activity of prenyltransferases. Compounds are effective inhibitors of tumor cells proliferation also. Invention describes also dimeric compounds comprising residues of compounds of the formulas (I) and (II) and a method of treatment of tumors or restenosis in patient that involves administration of these compounds to patient. EFFECT: valuable medicinal properties of compounds. 17 cl
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Authors
Dates
2002-08-10—Published
1997-05-06—Filed