THERAPEUTIC COMPOUNDS AND COMPOSITIONS Russian patent published in 2020 - IPC C07D417/06 C07D205/08 C07D401/06 C07D401/14 C07D405/14 C07D417/14 C07D409/06 A61K31/397 A61K31/4427 A61K31/443 A61P7/02 A61P7/10 

Abstract RU 2733405 C2

FIELD: pharmaceuticals.

SUBSTANCE: present invention refers to compounds of formula (II) and its pharmaceutically acceptable salts, where values R1-R7, A, X, Y are specified in the patent claim. Also disclosed are pharmaceutical compositions containing compounds of formula (II), which inhibit Factor XIa or kallikrein, and methods of using said compounds and compositions.

EFFECT: disclosed are therapeutic compounds and compositions.

38 cl, 10 dwg, 3 tbl, 27 ex

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RU 2 733 405 C2

Authors

Chrusciel Robert A.

Gadwood Robert C.

Hayward Neil J.

Melnick Michael J.

Navia Manuel

Poel Toni J.

Stewart Catherine A.

Stassen Frans L.

Dates

2020-10-01Published

2015-02-04Filed