FIELD: biotechnology, microbiology. SUBSTANCE: method is performed in continuous or semicontinuous regime using the strain Streptomyces clavuligerus ATCC 27064. Fermentation process is carried out under restrict control of soluble phosphate level in medium being both in the start and in the course of its. Lipids, preferably triglycerides, can be used as the carbon source. Method provides the significantly increased yield of clavulanic acid and/or its salts. EFFECT: improved method of preparing, increased yield. 8 cl, 5 tbl, 26 ex
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