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2 188 194

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IPC

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Application

98108027/04, 1996-10-02

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Start date

1996-10-02

(22)

Actual filing date

1996-10-02

(45)

Published

2002-08-27

(72)

Inventor

Kar'Jalajnen ArtoKhukhtala PaavoSavola Jukha-MattiVurster ZigfridEhloranta MajreKhillilja MaaritSakslund RajmoKokkroft ViktorKar'Jalajnen Ar'Ja

(73)

Holder

Orion Korporejshn

DERIVATIVES OF IMIDAZOLE AND PHARMACEUTICALLY ACCEPTABLE COMPOSITION Russian patent published in 2002 - IPC

Abstract RU 2188194 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of imidazole of the general formula (I) where n = 0 or 1; R₁ is hydrogen atom, alkyl; R₂ is hydrogen atom, or R₂ and R₃ form a double bond; R₃ is hydrogen atom, alkyl; R₄ is hydrogen atom, alkyl, hydroxy-group, alkoxy-group; R₅ is hydrogen atom or alkyl, or R₄ and R₅ form carboxyl group; R₆,R₇,R₈ are hydrogen atom, alkyl, hydroxy-group, alkoxy-group, hydroxyalkyl, halogen atom; X is -CHR₉-(CHR₁₀)_m- where m = 0 or 1; R₉ and R₁₀ mean hydrogen atom or alkyl. Compounds of the formula (I) show α₂--agonistic activity and therefore they can be used as an active component of a pharmaceutical composition. EFFECT: valuable medicinal property of compounds. 15 cl, 2 tbl

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RU 2 188 194 C2

Authors

Kar'Jalajnen Arto

Khukhtala Paavo

Savola Jukha-Matti

Vurster Zigfrid

Ehloranta Majre

Khillilja Maarit

Sakslund Rajmo

Kokkroft Viktor

Kar'Jalajnen Ar'Ja

Dates

2002-08-27—Published

1996-10-02—Filed