COMPOUNDS USEFUL AS TRPM8 MODULATORS Russian patent published in 2017 - IPC C07D231/40 C07D277/28 C07D333/20 C07D409/12 C07D409/14 C07D413/12 C07D471/04 A61K31/4155 A61K31/422 A61K8/49 A61P17/00 

Abstract RU 2608109 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to novel compounds of structural formula (II) and structural formula (III) or to salts thereof, compositions for inducing cooling effect, containing a compound having structural formula (I), formula (II) and formula (III), or salt thereof, a method of modulating agonistic activity of transient receptor potential melastatin 8 (TRPM8) channel and to a method of inducing a cooling sensation in a human or animal (versions).

EFFECT: novel compounds.

27 cl, 10 tbl, 253 ex

Similar patents RU2608109C2

Title Year Author Number
AMINOPHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT 2007
  • Kokhno Jasushi
  • Fudzhii Kijoshi
  • Saito Tatsukhiro
RU2430925C2
ANELLATED 9-HYDROXY-1,8-DIOXO-1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-7-CARBOXAMIDES - INTEGRASE INHIBITORS, METHODS FOR PREPARING AND USING THEREOF 2019
  • Ivashchenko Andrej Aleksandrovich
  • Ivashchenko Aleksandr Vasilevich
  • Mitkin Oleg Dmitrievich
  • Savchuk Nikolaj Filippovich
RU2717101C1
SUBSTITUTED 2-METHYLIDEN-5-(PHENYLAMINO)-2,3-DIHYDROTIOPHEN-3-ONE FOR TREATMENT OF LEUKEMIAS WITH TRANSLOCATIONS OF MLL-GENE AND OTHER ONCOLOGICAL DISEASES 2017
  • Kazyulkin Denis Nikolaevich
  • Korochkina Lyubov
RU2656603C1
DERIVATIVE OF 1",2",3"-TRIMETHOXIBENZO[5",6":5',4']1H-(aR,1S)-1-ACETAMIDO-6',7'-DIHYDROCYCLOHEPTA[2',3'-f]-2,3-DIHYDROFURAN AND ITS APPLICATION 2018
  • Fedorov Aleksej Yurevich
  • Shchegravina Ekaterina Sergeevna
  • Svirshchevskaya Elena Viktorovna
  • Gracheva Yuliya Aleksandrovna
RU2678440C1
FLUORINATED COMPOUND OF CYCLOPROPYLAMINE, THE METHOD OF PREPARATION, THE PHARMACEUTICAL COMPOSITION AND ITS USE 2017
  • Liu, Khong
  • Li, Dzhia
  • Vang, Dzhiang
  • Su, Mingbo
  • Vang, Skhuni
  • Zkhou, Yuubo
  • Zkhu, Vei
  • Ksyu, Vei
  • Li, Kkhunpu
  • Dzhiang, Khualiang
  • Chen, Kaiksian
RU2746323C2
BENZAMIDE DERIVATIVES HAVING ANTICANCER ACTIVITY, METHODS FOR PRODUCTION THEREOF AND USE THEREOF 2011
  • Baj Khua
  • Chzhao Sjujjan
  • Gun Junsjan
  • Chzhun Tszin'Tsin
  • Chzhu Tsifehn
  • Lju Sjaojuj
  • Lju Lifehj
  • Chzhou Tsisjan'
RU2565079C2
AMINO ALCOHOL DERIVATIVES 2005
  • Khattori Koudzi
  • Toda Susumu
  • Vasizuka Keniti
  • Ito Sindzi
  • Tanabe Daisuke
  • Araki Takanobu
  • Sakurai Minoru
RU2399614C2
AMINO ALCOHOL AND IMMUNODEPRESSANT CONTAINING IT AS ACTIVE INGREDIENT 2007
  • Kokhno Jasushi
  • Fudzhii Kijoshi
  • Saito Tatsukhiro
  • Kurijama Kazukhiko
  • Jasue Tokutarou
RU2458044C2
METHOD OF TREATMENT OR PREVENTION OF PHYSIOLOGICAL AND/OR PATHOPHYSIOLOGICAL CONDITIONS MEDIATED BY GROWTH HORMONE SECRETION STIMULATING RECEPTORS, TRIAZOLE AND BASED PHARMACEUTICAL COMPOSITION 2006
  • Beglen Dam'En
  • Demanzh Ljuk
  • Martine Zhan
  • Mulen Alin
  • Perrissoud Daniehl'
  • Ferents Zhan-Alen
RU2415134C9
COMPOUNDS FOR TREATING CANCER 2011
  • Dolton Dzhejms T.
  • Miller Duejn D.
  • Li Chien-Min
  • An Suntszo
  • Lu Yan
  • Van Chzhao
  • Chen Tszyantszun
  • Li Vej
  • Dyuk Charlz
RU2609018C2

RU 2 608 109 C2

Authors

Prist Chad

Nonkovich Alen

Petron Endryu

Ung Dzhejn

Dates

2017-01-13Published

2011-11-04Filed