FIELD: chemistry.
SUBSTANCE: present invention relates to novel compounds of structural formula (II) and structural formula (III) or to salts thereof, compositions for inducing cooling effect, containing a compound having structural formula (I), formula (II) and formula (III), or salt thereof, a method of modulating agonistic activity of transient receptor potential melastatin 8 (TRPM8) channel and to a method of inducing a cooling sensation in a human or animal (versions).
EFFECT: novel compounds.
27 cl, 10 tbl, 253 ex
Title | Year | Author | Number |
---|---|---|---|
AMINOPHOSPHATE DERIVATIVE AND S1P RECEPTOR MODULATOR CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | 2007 |
|
RU2430925C2 |
ANELLATED 9-HYDROXY-1,8-DIOXO-1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-7-CARBOXAMIDES - INTEGRASE INHIBITORS, METHODS FOR PREPARING AND USING THEREOF | 2019 |
|
RU2717101C1 |
SUBSTITUTED 2-METHYLIDEN-5-(PHENYLAMINO)-2,3-DIHYDROTIOPHEN-3-ONE FOR TREATMENT OF LEUKEMIAS WITH TRANSLOCATIONS OF MLL-GENE AND OTHER ONCOLOGICAL DISEASES | 2017 |
|
RU2656603C1 |
DERIVATIVE OF 1",2",3"-TRIMETHOXIBENZO[5",6":5',4']1H-(aR,1S)-1-ACETAMIDO-6',7'-DIHYDROCYCLOHEPTA[2',3'-f]-2,3-DIHYDROFURAN AND ITS APPLICATION | 2018 |
|
RU2678440C1 |
FLUORINATED COMPOUND OF CYCLOPROPYLAMINE, THE METHOD OF PREPARATION, THE PHARMACEUTICAL COMPOSITION AND ITS USE | 2017 |
|
RU2746323C2 |
BENZAMIDE DERIVATIVES HAVING ANTICANCER ACTIVITY, METHODS FOR PRODUCTION THEREOF AND USE THEREOF | 2011 |
|
RU2565079C2 |
AMINO ALCOHOL DERIVATIVES | 2005 |
|
RU2399614C2 |
AMINO ALCOHOL AND IMMUNODEPRESSANT CONTAINING IT AS ACTIVE INGREDIENT | 2007 |
|
RU2458044C2 |
METHOD OF TREATMENT OR PREVENTION OF PHYSIOLOGICAL AND/OR PATHOPHYSIOLOGICAL CONDITIONS MEDIATED BY GROWTH HORMONE SECRETION STIMULATING RECEPTORS, TRIAZOLE AND BASED PHARMACEUTICAL COMPOSITION | 2006 |
|
RU2415134C9 |
COMPOUNDS FOR TREATING CANCER | 2011 |
|
RU2609018C2 |
Authors
Dates
2017-01-13—Published
2011-11-04—Filed