FIELD: organic chemistry, molecular biology, virology, medicine. SUBSTANCE: invention relates to a novel derivative of 2',3'-dideoxy-2',3'-didehydrothymidine (d4T), i. e. 2',3'-didehydro-2',3'-dideoxy-thymidine-5'-[(ethoxycarbonyl)(ethyl)phosphonate] as an inhibitor of human immunodeficiency virus (HIV). An antiviral activity of the novel compound with respect to HIV exceeds that of d4T. EFFECT: enhanced antiviral activity. 1 dwg, 1 tbl
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