METHOD FOR DETERMINING OPTIMUM SORBENT TYPE AND SORPTION TIME REQUIRED FOR CLEANING ORGANISM IN CARRYING OUT PLASMOSORPTION Russian patent published in 2002 - IPC

FIELD: medicine. SUBSTANCE: method involves determining initial marker substance concentration C₀ in patient blood plasma. The plasma is distributed over 4xN test tubes, where N is the number of sorbents under test. Equal quantities of each sorbent are added to plasma in 4 test tubes and incubation is carried out for 5,10, 15 and 20 min, respectively. Then, marker substance C_i,k concentration in plasma is to be determined, where k is the number of sorbent under test and i is the test tube number in each set. Concentration difference is calculated from formula S_1,k = C_1,k-C₀, S_i,k = C_i,k-C_i-1,k. Minimum value of index i varying from 1 to 3 is to be found so that one of relationships S_i+1,k<0, |S_i,k|/10>|S_i+1,k|, is to be satisfied, The value is denoted as m(k) and C_m(k),k. values are to be compared. The sorbent which C_m(k),k is found to reach minimum value is considered to be optimum for sorption. The sorption time is thought to be equal to 5 min multiplied by m(k). EFFECT: enhanced effectiveness of treatment. 2 tbl