METHOD OF SYNTHESIS OF 2,5,8-TRIHYDROXY-6,7-DICHLORO-3-ETHYL-1,4-NAPHTHOQUINONE Russian patent published in 2002 - IPC

Abstract RU 2193550 C1

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to the improved method of synthesis of 2,5,8-trihydroxy-6,7-dichloro-1,4-naphthoquinone by cycloacylation of 1,2,4-trimethoxy-3,5-diethyl- -benzene with dichloromaleic anhydride in the presence of aluminum chloride and sodium chloride. 1,2,4-Trimethoxy-3,5-diethylbenzene is synthesized by reduction of 3,5-diacetyl-1,2,4-trihydroxybenzene to 1,2,4-trihydroxy-3,5- diethylbenzene and its the following exhaustive methylation. Method provides preparing the end substance with yield 59% and excludes the use of fire hazard reagents used in synthesis of the parent compound. EFFECT: improved method of synthesis. 5 sch

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RU 2 193 550 C1

Authors

Anufriev V.F.

Balaneva N.N.

Malinovskaja G.V.

Pokhilo N.D.

Chizhova T.L.

Dates

2002-11-27Published

2001-03-05Filed