METHOD OF PREPARING GANGLIOSIDES Russian patent published in 2002 - IPC

Abstract RU 2195296 C2

FIELD: pharmaceutical chemistry. SUBSTANCE: phospholipid-free gangliosides that can be used as drugs are prepared by homogenization and acetone-assisted dehydration of gray matter followed by extraction with chloroform-acetone mixture and subsequent acetone (5:1)- mediated isolation of desired product, supernatant being preliminarily purified by acetone at ratio (1.5-2.0): 1 and filtered before isolation pf product. EFFECT: enabled removal of phospholipids without losses in specific biological activity of gangliosides. 4 ex

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RU 2 195 296 C2

Authors

Efremenko V.I.

Overchenko V.V.

Misetova E.N.

Zhilchenko E.B.

Savel'Eva I.V.

Taran T.V.

Efremenko D.V.

Dates

2002-12-27Published

2000-04-12Filed