METHOD FOR DIAGNOSING CRYOGENIC INJURY SEVERITY DEGREE Russian patent published in 2003 - IPC

FIELD: medicine. SUBSTANCE: method involves determining anticoagulation factor concentration in patient blood plasma like antithrombin III and α₂-macroglobulin in particular, to diagnose cryogenic injury severity degree. Antioxidation factors contents, biologically active amine system and immune system state are additionally determined. The cryogenic injury severity degree is diagnosed by interpreting the synotoxic adaptation program activity coefficient (SAPAC) calculated from formula: , where A is the relative antithrombin III activity, %; A_gao is the relative plasma antioxidation activity, %; C_ach is the relative acetylcholine blood concentration, nmole/l; C_IgM is the relative immunoglobulin M blood concentration; C_α2-mg is the relative α₂-macroglobulin concentration, mcmole/l; C_mda is the relative malonic dialdehyde concentration, mcmole/l; C_cch is the relative catecholamines concentration, mcg/l; C_IgA is the relative immunoglobulins A concentration, mcmole/l which values are interpreted in terms of injury severity degree. General antioxidation plasma and malonic dialdehyde activity values are taken as the antioxidation factors. Acetylcholine and catecolamines concentrations are taken as biologically active amine system properties. Immunoglobulins A and M concentrations are taken as immune system characteristics. EFFECT: enhanced accuracy of diagnosis. 4 cl, 1 tbl