PEPTIDE FRAGMENTS OF BASIC PROTEIN MYELIN, PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF AND APPLICATION OF THESE COMPOSITIONS FOR TREATMENT OF CEREBROSPINAL SCLEROSIS Russian patent published in 2003 - IPC

Abstract RU 2198893 C2

FIELD: organic chemistry, proteins, biochemistry. SUBSTANCE: invention describes peptide of the formula: Asp-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr- - Pro-Arg-Thr that is able to neutralize or modulate formation of antimyelin basic protein. Peptide can be used for treatment of patients with cerebrospinal sclerosis and it exhibits the more activity as compared with that of myelin basic protein. Peptide does not exhibit toxicity and immunogenic properties. Invention describes also pharmaceutical composition comprising peptide and method of treatment of patients with cerebrospinal sclerosis. EFFECT: improved method of treatment, valuable medicinal properties of peptide and composition. 8 cl, 4 tbl, 35 dwg, 10 ex

Similar patents RU2198893C2

Title Year Author Number
PEPTIDE SPECIFICITY OF ANTIBODY TO MYELIN BASIC PROTEIN, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND METHOD OF TREATMENT OF PATIENTS WITH CEREBROSPINAL SCLEROSIS 1995
  • Uarren Kennet
  • Kehtz Ingrid
RU2157815C2
PHARMACEUTICAL COMPOSITION AND A METHOD OF TREATMENT OF PATIENTS WITH CEREBROSPINAL SCLEROSIS 1992
  • Uorren Kennet G.
  • Kats Ingrid
RU2121850C1
METHOD OF TREATING MULTIPLE SCLEROSIS 2005
  • Frona Pol A.
RU2384345C2
LIPOSOMES CONTAINING OLIGOPEPTIDES - FRAGMENTS OF MYELIN BASIC PROTEIN, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING MULTIPLE SCLEROSIS 2009
  • Avtushenko Sergej Sergeevich
  • Surkov Kirill Gennadievich
  • Romanov Vadim Dmitrievich
  • Genkin Dmitrij Dmitrievich
  • Gabibov Aleksandr Gabibovich
  • Belogurov Aleksej Anatol'Evich
  • Ponomarenko Natal'Ja Aleksandrovna
RU2448685C2
PEPTIDE FROM THE COMPOSITION OF THE IMMUNOGLOBULIN HUMAN HEAVY CHAIN, SUITABLE FOR TREATMENT OF MULTIPLE SCLEROSIS 2016
  • Turobov Valerij Igorevich
  • Danilkovich Aleksej Viktorovich
  • Shevelev Aleksej Borisovich
  • Biryukova Yuliya Konstantinovna
  • Azev Vyacheslav Nikolaevich
  • Murashev Arkadij Nikolaevich
  • Lipkin Valerij Mikhajlovich
  • Udovichenko Igor Petrovich
RU2646817C1
METHOD FOR TREATING MULTIPLE SCLEROSIS 2015
  • Garren Khideki
  • Pfefen Zhan-Pol
  • Li-Kvai-Cheung Anne-Mari
  • Libonati Mikele
RU2757961C2
PEPTOID LIGANDS FOR AUTOIMMUNE T-CELL RECOVERY AND PROCESSING 2010
  • Gok Ehnn R.
  • Udugamasoorija D. Gomika
  • Kodehdek Tomas
RU2563822C2
COMPOSITIONS FOR TREATMENT OF DISSEMINATED SCLEROSIS 2008
  • Fussa Arno
RU2492234C2
T-CELLULAR VACCINE FOR CEREBROSPINAL SCLEROSIS TREATMENT 1998
  • Vejner Lesli P.
  • Korreale Khorkhe D.
RU2209633C2
THERAPY OF INFLAMMATORY DISEASES 2007
  • Soliven Behtti K.
RU2440110C2

RU 2 198 893 C2

Authors

Uorren Kennet G.

Kehtts Ingrid

Dates

2003-02-20Published

1998-04-03Filed