FIELD: microbiology, antibiotics. SUBSTANCE: strain Strepromyces nodosus 472 VNIISCHM D-666 is obtained by selection method by effect with mutagens N-nitrosomethylurea and N-nitroso-N-methylbiuret. Strain shows the enhanced productivity of amphotericin B that is effective antifungal antibiotic used in medicinal practice for treatment of deep and systemic mycosis. EFFECT: increased yield of amphotericin B.
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Authors
Dates
2003-02-20—Published
2000-12-13—Filed