STRAIN STREPTOMYCES NODOSUS 472 VNIISCHM D-666 AS PRODUCER OF AMPHOTERICIN B Russian patent published in 2003 - IPC

Abstract RU 2198928 C2

FIELD: microbiology, antibiotics. SUBSTANCE: strain Strepromyces nodosus 472 VNIISCHM D-666 is obtained by selection method by effect with mutagens N-nitrosomethylurea and N-nitroso-N-methylbiuret. Strain shows the enhanced productivity of amphotericin B that is effective antifungal antibiotic used in medicinal practice for treatment of deep and systemic mycosis. EFFECT: increased yield of amphotericin B.

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RU 2 198 928 C2

Authors

Malkov M.A.

Polatovskaja O.G.

Pronina M.I.

Fadeeva I.P.

Kaminskaja A.Ju.

Dolinova O.I.

Dates

2003-02-20Published

2000-12-13Filed