FIELD: organic chemistry, chemical technology, medicine, pharmacy. SUBSTANCE: invention relates to novel amides of pyridylalkene and pyridylalkyne acids. Invention describes amides of pyridylalkene and pyridylalkyne acids of the general formula (I): 
where radicals R1, R2, R3, R4, A, D, E, G and k are given in claim 1 of the invention claim. Invention describes also method (VERSIONS) of synthesis of amides of pyridylalkene and pyridylalkyne acids, pharmaceutical composition based on compounds of the formula (I) eliciting antineoplastic and/or immunosuppression activity and method of pharmaceutical composition preparing. Invention provides synthesis of novel compounds eliciting valuable biological properties. EFFECT: improved methods of synthesis and preparing, valuable medicinal properties of compounds. 35 cl, 10 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOUND AIMED AT PROTEIN AND DEGRADATION THEREOF, AND METHOD FOR PRODUCTION AND USE THEREOF | 2021 |
|
RU2829459C1 |
| POLYCYCLIC THIAZOLIDINE-2-YLIDENE AMINES, MEDICINAL AGENTS CONTAINING THEREOF AND METHOD FOR PREPARING MEDICINAL AGENT | 1999 |
|
RU2236405C2 |
| NOVEL DERIVATIVES OF IMIDAZOLIDINE, THEIR PREPARING, THEIR APPLICATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEREOF | 1998 |
|
RU2213737C2 |
| AGENT FOR PROTECTION OF CULTURED PLANTS FROM PHYTOTOXIC ADVERSE EFFECT OF HERBICIDES, N- ACYLSULFONAMIDES | 1997 |
|
RU2182423C2 |
| AMINOBENZOPHENONES | 2002 |
|
RU2361855C2 |
| PHARMACEUTICAL AGENT CONTAINING INHIBITOR OF SODIUM-DEPENDENT PHOSPHATE CARRIER | 2015 |
|
RU2740008C2 |
| SUBSTITUTED DERIVATIVES OF IMIDAZOLIDINE, METHOD FOR PREPARING AND PHARMACEUTICAL PREPARATION | 1998 |
|
RU2239641C2 |
| NEW FIVE-MEMBER HETEROCYCLES, THEIR PREPARING, THEIR APPLYING AND PHARMACEUTICAL PREPARATIONS COMPRISING THEREOF | 1998 |
|
RU2240326C2 |
| ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYLAMINES AND THEIR USING AS PHARMACEUTICAL PREPARATIONS | 2002 |
|
RU2301797C2 |
| N-GUANIDINOALKYLAMINES, PRODUCTION, USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | 2000 |
|
RU2253651C2 |
