MULTI-SPECIFIC OR BISPECIFIC MOLECULE (VERSIONS), METHOD FOR ELIMINATION OR DECREASING QUANTITY OF TARGET CELLS IN SUBJECT'S BODY, METHOD FOR TREATING PATHOGEN-INFECTED SUBJECT AND METHOD FOR SUBJECT'S VACCINATION Russian patent published in 2003 - IPC

Abstract RU 2201766 C2

FIELD: medicine. SUBSTANCE: innovation deals with multi-specific compounds containing, at least, one binding determinant which binds Fc-alpha-receptors at effector cell. Another binding determinant binds one or more antigens at target cell, for example Neu/Her-2 protooncogene product or receptor of epidermal growth factor at cancer cells, or Candida antigens at infected cells. Examples are bispecific and trispecific antibodies. It is suggested both therapeutic and prophylactic application of mentioned compounds. The method enables to achieve multiple specificity in treating cancer and pathogenic infections. EFFECT: higher efficiency. 19 cl, 28 dwg

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RU 2 201 766 C2

Authors

Gratsiano Robert

Deo Jashvont M.

Keler Tibor

Dates

2003-04-10—Published

1997-07-10—Filed