FIELD: medicine. SUBSTANCE: the innovation deals with obtaining bandage materials for treating purulentnecrotic wounds of different etiology. Bandage material contains, simultaneously, trypsin proteolytic enzyme and antioxidants with different physical properties: dieton and mexidol. The former is water-insoluble and it is immobilized out of dimethysulfoxide solution. At the second stage trypsin should be chemically combined with carrier (dialdehydecellulose). At the third stage material should be impregnated with mexidol solution. At applying a napkin made of such a material mexidol enters wound secrete, maintenance dose of difficultly soluble dieton enters the wound for the prolonged period of time. Trypsin purifies the wound against detritus due to covalent addition during the whole period of napkin's application (up to 72 h). Curative effect at applying trypsincontaining bandage material along with two different antioxidants increases by 1.5 times the effect obtained at applying trypsin and dieton only or trypsin and mexidol only. EFFECT: higher efficiency. 1 cl, 1 tbl
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Authors
Dates
2003-05-10—Published
2000-11-20—Filed