2,2,6,6-TETRAKIS-(TRIFLUOROMETHYL)-4-ETHYLAMINO-5,6-DIHYDRO-1,3,5-OXADIAZINE ("SYNTHAZIN"), METHOD OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2003 - IPC

Abstract RU 2203892 C1

FIELD: organic chemistry, medicine, oncology, pharmacy. SUBSTANCE: invention relates to novel fluoro-derivative of 1,3,5-oxadiazine eliciting the expressed antitumor effect relative to breast adenocarcinoma cells. Invention describes 2,2,6,6-tetrakis-(trifluoromethyl)-4-ethylamino-5,6-dihydro-1,3,5-oxadiazine of the formula: . Invention proposes also method of its synthesis and pharmaceutical composition based on thereof. Invention provides preparing the novel compound eliciting valuable biological properties. EFFECT: improved method of synthesis, valuable medicinal properties. 3 cl, 1 tbl, 3 ex

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RU 2 203 892 C1

Authors

Belushkina N.N.

Ivanov A.A.

Krjukov L.N.

Krjukova L.Ju.

Moskaleva E.Ju.

Pal'Tsev M.A.

Posypanova G.A.

Severin E.S.

Severin S.E.

Torgun I.N.

Fel'Dman N.B.

Khomjakov Ju.N.

Dates

2003-05-10Published

2001-10-12Filed