4-NITRO-3-FLUOROMETHYLPERFLUORONONANOYLANILIDE (FLUSTAT), METHOD IF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2002 - IPC

Abstract RU 2186057 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes the novel chemical compound: 4-nitro-3-trifluoromethyl-perfluorononanoylanilide and method of its synthesis. Method involves the acylation reaction of 4-nitro-3-trifluoromethylaniline with perfluoro- -pelargonic acid chloroanhydride. Invention relates to also a pharmaceutical composition comprising 4-nitro-3-trifluoromethyl- - nonanoylanilide as an active component taken in effective dose and showing an anti-androgenic activity. EFFECT: new compound indicated above, improved method of synthesis. 4 cl, 3 tbl, 5 ex

Similar patents RU2186057C1

Title Year Author Number
2,2,6,6-TETRAKIS-(TRIFLUOROMETHYL)-4-ETHYLAMINO-5,6-DIHYDRO-1,3,5-OXADIAZINE ("SYNTHAZIN"), METHOD OF ITS SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2001
  • Belushkina N.N.
  • Ivanov A.A.
  • Krjukov L.N.
  • Krjukova L.Ju.
  • Moskaleva E.Ju.
  • Pal'Tsev M.A.
  • Posypanova G.A.
  • Severin E.S.
  • Severin S.E.
  • Torgun I.N.
  • Fel'Dman N.B.
  • Khomjakov Ju.N.
RU2203892C1
4-NITRO-2-TRIFLUOROMETHYLHEPTADECAFLUORONONANOYLANILIDE (ALPAXINE), METHOD FOR ITS PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2002
  • Alferov A.V.
  • Panov A.E.
  • Pomazkova T.A.
  • Krjukova L.Ju.
  • Sukojan G.V.
  • Vorontsov E.A.
  • Kuznetsov S.L.
  • Krjukov L.N.
RU2224743C1
POLYMER CONTAINING MEDICINAL AGENT BASED ON ANTITUMOR AGENT ETOPOSIDE 2015
  • Vorontsov Evgenij Alekseevich
  • Gorshkova Lada Borisovna
  • Gukasova Nadezhda Vadimovna
  • Kuznetsov Sergej Leonidovich
  • Moskaleva Elizaveta Yurevna
  • Muraveva Anna Ivanovna
  • Posypanova Galina Aronovna
  • Rodina Alla Valerevna
  • Tubasheva Irina Anatolevna
  • Severin Sergej Evgenevich
RU2595859C1
QUINOLINE DERIVATIVES FOR CORRECTION OF HEMOSTASIS SYSTEM, PHARMACEUTICAL COMPOSITION, AGENT FOR HEMOSTASIS CORRECTION 2000
  • Severin E.S.
  • Severin S.E.
  • Khomjakov Ju.N.
  • Krjukov L.N.
  • Dukhanin A.S.
  • Vorontsov E.A.
  • Krylov I.I.
  • Kuznetsov S.L.
RU2177317C1
ANTIMICROBIAL MEDICINAL AGENT, METHOD OF PRODUCTION OF DIRECTIONAL MEDICINAL AGENT CONTAINIG NANOPARTICLES 2007
  • Severin Evgenij Sergeevich
  • Krjukov Leonid Nikolaevich
  • Vorontsov Evgenij Alekseevich
  • Kuznetsov Sergej Leonidovich
  • Pomazkova Tat'Jana Anatol'Evna
RU2327459C1
ANTICANCER DRUG BASED ON NICLOSAMIDE 2016
  • Vorontsov Evgenij Alekseevich
  • Gukasova Nadezhda Vadimovna
  • Zhirnik Aleksandr Sergeevich
  • Kuznetsov Sergej Leonidovich
  • Moskaleva Elizaveta Yurevna
  • Tubasheva Irina Anatolevna
  • Posypanova Galina Aronovna
  • Rodina Alla Valerevna
RU2617049C1
CONJUGATE OF BIOLOGICALLY ACTIVE SUBSTANCES WITH $$$-FETOPROTEIN SHOWING THE SELECTIVE ACTION WITH RESPECT TO CANCER TUMORS, METHOD OF THEIR PREPARING (VARIANTS) AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1996
  • Luzhkov Jurij Mikhajlovich[Ru]
  • Moskaleva Elizaveta Jur'Evna[Ru]
  • Nakash'Jan Rajmond[Es]
  • Posypanova Galina Aronovna[Ru]
  • Rodina Alla Valer'Evna[Ru]
  • Severin Evgenij Sergeevich[Ru]
  • Severin Sergej Evgen'Evich[Ru]
  • Fel'Dman Natalija Borisovna[Ru]
  • Finakova Galina Vasil'Evna[Ru]
  • Shmyrev Igor' Igorevich[Ru]
RU2071351C1
PEPTIDE REPRESENTING ANALOG OF ALPHA-FETOPROTEIN FRAGMENT, CONJUGATE OF PEPTIDE WITH DOXORUBICIN AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF FOR TREATMENT OF ONCOLOGY DISEASE 2006
  • Severin Evgenij Sergeevich
  • Posypanova Galina Aronovna
  • Makarov Vladimir Alekseevich
  • Kireeva Natal'Ja Nikolaevna
  • Severin Sergej Evgen'Evich
RU2317102C1
POLYPEPTIDE DISPLAYING ANALOG OF RECEPTOR-BINDING EPIDERMAL GROWTH FACTOR FRAGMENT FROM 21 TO 31 AMINO ACIDS, ITS CONJUGATE WITH DOXORUBICIN AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2001
  • Kiselev S.M.
  • Lutsenko S.V.
  • Severin E.S.
  • Severin S.E.
  • Fel'Dman N.B.
RU2196604C1
COMPOSITION FOR TREATMENT OF PULMONARY INFECTION 2001
  • Gel'Perina S.Eh.
  • Guljaev Aleksandr Evgen'Evich
  • Ivanov A.A.
  • Pal'Tsev M.A.
  • Severin E.S.
  • Severin S.E.
  • Skidan I.N.
RU2185818C1

RU 2 186 057 C1

Authors

Aljautdin R.N.

Vorontsov E.A.

Ivanov A.A.

Krjukov L.N.

Kuznetsov S.L.

Moskaleva E.Ju.

Pal'Tsev M.A.

Posypanova G.A.

Severin E.S.

Severin S.E.

Khomjakov Ju.N.

Dates

2002-07-27Published

2001-03-22Filed