PHARMACEUTICAL COMPOSITIONS Russian patent published in 2003 - IPC

Abstract RU 2204387 C2

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition comprising as active component 2-amino-2-[2-(4-octylphenyl)ethyl] -propane-1,3-diol or its pharmaceutically acceptable salt with acid taken in the amount 0.01-20 wt.% as measure for composition weight. As stabilizing agent the composition comprises cyclodextrin taken in the amount 1-50 weight p. p. per weight p. of indicated active component. If necessary, the composition comprises saccharide. Composition can be prepared as liquid agent being without precipitation of crystals of indicated active component. Composition is useful for suppression of organ or bone marrow rejection in transplantation, immunodepression maintaining therapy or treatment of autoimmune diseases. Composition shows antifoaming action and shows less adverse effects as, for example, hemolysis or topical irritation. EFFECT: valuable medicinal properties of composition. 15 cl, 7 ex

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RU 2 204 387 C2

Authors

Sakai Atsusi

Fudzii Tsuneo

Masuda Rumiko

Misina Tadasi

Tiba Kendzi

Dates

2003-05-20Published

1999-01-19Filed