FIELD: medicine, pharmacy. SUBSTANCE: invention relates to composition (variants) including vegetable sterol and soybean protein matter and/or isoflavone taken among genistein, daidzein, glycetein, biochanin A, formononetin and their natural glycosides being vegetable sterol comprises at least 0.49% of composition weight. Invention represents also method of reduction of blood total and low density lipoprotein chlolesterol content in humans (variants) where vegetable sterol and soybean protein matter and/or isoflavone are prescribed to humans (simultaneously). The dose of vegetable sterol is at least 0.49% of total weight of vegetable sterol and soybean matter and/or isoflavone. Invention relates also to method of prophylaxis or minimization of atherosclerosis development in human that involves prescription of vegetable sterol and soybean matter and/or isoflavone to humans in combination (simultaneously) being the dose of vegetable sterol is at least 0.49% of total weight of vegetable sterol and soybean protein matter and/or isoflavone. Invention provides reduction of risk of atherosclerosis and coronary insufficiency development in humans. EFFECT: enhanced effectiveness and valuable medicinal properties of composition. 32 cl, 4 dwg
