AMIDES OF ACIDS, METHOD FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 2003 - IPC

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention relates to novel amides of acids of the formula (I): where R¹ means C₁-C₆-alkanoyl, C₁-C₆-alkoxycarbonyl, benzoyl, benzoyl substituted with halogen-(C₁-C₆)-alkoxy-group, C₁-C₆-alkylsulfonyl, phenylsulfonyl, phenylsulfinyl substituted with halogen atom or cyclo--(C₃-C₆)-alkylcarbonyl; R²- means phenyl, phenyloxy- or phenylamino-group where each phenyl can be substituted with halogen atom, pyridyl or pyridylamino-group; A represents a simple bond; E means ethylene; X represents CH; Y means NR⁵ where R⁵ is hydrogen atom; Q represents C(O) or -SO₂-; R³ and R⁴ taken in common form ethylene, or their pharmaceutically acceptable salts. Compounds of the formula (I) can be used for treatment and/or prophylaxis of the central nervous system diseases, such as amnesia, schizophrenia or feeble- mindedness. EFFECT: improved preparing method, valuable medicinal properties of compounds. 8 cl, 1 tbl