DERIVATIVES OF BENZAZEPINON-N-ACETIC ACID SUBSTITUTED WITH PHOSPHONIC ACID, METHOD FOR THEIR PREPARING AND MEDICINAL AGENTS CONTAINING THESE COMPOUNDS Russian patent published in 2003 - IPC

Abstract RU 2211219 C2

FIELD: organic chemistry, medicine, biochemistry, pharmacy. SUBSTANCE: invention relates to novel derivatives of benzazepinon-N-acetic acid substituted with phosphonic acid that are pharmaceutically active compounds. Invention describes derivatives of benzazepinon-N-acetic acid substituted with phosphonic acid of the general formula (I): wherein R¹, R², R³ mean hydrogen atom or group forming biolabile phosphonic acid ester and physiologically acceptable salts of acids of the formula (I). Invention describes also a medicinal agent exhibiting inhibitory effect on activity of endopeptidase of the central nervous system and containing compound of the formula (I) and method for preparing compounds of the formula (I). Invention provides the development of novel pharmaceutically active substances. EFFECT: improved preparing method, valuable medicinal properties of compounds. 4 cl, 3 tbl, 34 ex

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RU 2 211 219 C2

Authors

Val'Dek Kharal'D

Majl' Jorg

Tormelen Dirk

Vurl' Mikhel'

Dates

2003-08-27—Published

1998-11-11—Filed