N-[ALKOXYPOLY(ETHYLENEOXY)CARBONYLMETHYL]-AMMONIUM CHLORIDES ELICITING FUNGISTATIC AND BACTERICIDAL ACTIVITY AND METHOD FOR THEIR PREPARING Russian patent published in 2003 - IPC

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to N-[alkoxypoly(ethyleneoxy)- carbonylmethyl]ammonium chlorides of the formula (I) eliciting fungistatic and bactericidal activity and to method for their preparing. In compounds of the formula (I) at R is alkyl-C₈-C₁₀; R¹ = R² is CH₃; R³ is alkyl-C₁₀-C₁₆; n = 3 (mean degree of oxyethylation); at R is alkyl-C₁₂-C₁₄; R¹ = R² = R³ is alkyl-C₇-C₉; n = 20 (mean degree of oxyethylation); at R is alkyl-C₁₂-C₁₄; R¹ = R² is hydrogen atom; R³ is C₁₆H₃₃; n = 10 (mean degree of oxyethylation); at R is alkyl-C₁₂-C₁₄; R¹ = R² is hydrogen atom; R³ is alkyl-C₁₀-C₁₆; n = 10 (mean degree of oxyethylation). Method for preparing involves interaction of monochloroacetic acid with alkoxypolyethylene glycols of the general formula: RO(CH₂CH₂O)_nH wherein: at R is alkyl-C₈-C₁₀; n = 3 (mean degree of oxyethylation); at R is alkyl-C₁₂-C₁₄; n = 10, 20 in the presence of acidic catalyst, such as cation-exchange resin KU-2 in H⁺- form, in boiling solvent medium, for example, toluene, with azeotropic removal of formed water and the following treatment of prepared product with amine at heating of the general formula (II) wherein: at R¹ = R² is CH₃; R³ is alkyl-C₁₀-C_16/ ; at R¹ = R² is hydrogen atom; R³ is C₁₆H₃₃; at R¹ = R² is hydrogen atom; R³ is alkyl-C₁₀-C₁₆; or R¹ = R² = R³ is alkyl-C₇-C₉. Compounds of the formula (I) can be used for control of fungal and bacterial damages in medicine, veterinary science and agriculture. EFFECT: improved preparing method, valuable properties of compounds. 2 cl, 2 tbl