[(AMMONIA)METHYLCARBONYLOXYPOLY(ALKLYLENEOXY)]-PROPANE CHLORIDES HAVING BACTERICIDAL ACTIVITY AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2007 - IPC C08G65/333 C08G65/32 A61K31/765 

FIELD: organic chemistry.

SUBSTANCE: invention relates to compounds of general formula , wherein: when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=aliphatic C₁₇-C₂₀-hydrocarbon radical, a+c+e = 49, b+d+f = 9, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=aliphatic C₁₇-C₂₀-hydrocarbon radical, a+c+e = 55, b+d+f = 10, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³= C₁₆H₃₃, a+c+e = 49, b+d+f = 9, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 55, b+d+f = 10, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H, R³=C₁₆H₃₃, a+c+e = 66, b+d+f = 15, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 76, b+d+f = 18, n = 3; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 49, b+d+f = 9, n = 1; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 55, b+d+f = 10, n = 1; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 49, b+d+f = 0, n = 1; when X=Y=Z=R¹R²R³N⁺, R¹=R²=H R³=C₁₆H₃₃, a+c+e = 55, b+d+f = 0, n = 1. Also disclosed is method for production of abovementioned compounds by interaction of 1,2,3-tris[hydroxypoly(alkyleneoxy)]-propanes with monochloroacetic acid in presence of acetic catalyst in medium of boiling organic solvent with azeotropic removing of formed water followed by treatment at heating of obtained product in polar solvent medium with amine compounds of formula R¹R²R³N, wherein R¹=R²=H; R³=C₁₆H₃₃, aliphatic C₁₇-C₂₀-hydrocarbon radical, in molar ratio of hydroxy propane derivative: monochloroacetic acid:amine compound = 1:3.0-3.2:3.0-3.2, respectively.

EFFECT: new compounds with bactericidal activity.

7 cl, 1 tbl, 10 ex