PIPERAZINE-CYCLODEXTRIN COMPLEX AND MEDICINAL AGENT CONTAINING INDICATED COMPLEX Russian patent published in 2003 - IPC

Abstract RU 2216549 C2

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes piperazine-cyclodextrin complex formed by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl] -ethyl] -5,6-dimethoxy-1-(4- imidazolylmethyl)- -1H- indazole and water-soluble derivative of cyclodextrin where indicated derivative of cyclodextrin represents sulfobutyl-β--cyclodextrin either hydroxyl-β-cyclodextrin or its salt. Invention describes also agent for treatment of diseases of circulation and brain diseases that comprises above indicated complex as an active component. Complex shows high solubility in water and low topical irritating effect. EFFECT: improved and valuable medicinal properties of complex. 13 cl, 3 tbl

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RU 2 216 549 C2

Authors

Kikuti Masakhiko

Nagase Jukikhiko

Uekama Kaneto

Dates

2003-11-20Published

1998-10-29Filed