FIELD: medicine, biochemistry, pharmacy. SUBSTANCE: invention relates to preparing new biologically active compounds and creation of medicinal agents based on thereof. Invention proposes glycoproteins isolated from intercellular space tissue of different organs, serum blood, human and animals bile isolated by isoelectric focusing method that are soluble in saturated (100%) ammonium sulfate solution and having the apparent molecular mass 10-45 kDa. Such glycoproteins elicit biological activity in super small doses 10-12-10-29 mole/l and below. Invention proposes also pharmaceutical compositions comprising indicated glycoproteins taken in effective dose and pharmaceutically acceptable carrier. EFFECT: valuable medicinal properties of glycoproteins. 4 cl, 8 tbl, 29 dwg, 17 ex
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