DERIVATIVES OF ACRIDINE AND METHOD FOR THEIR PREPARING Russian patent published in 2004 - IPC

FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention describes derivatives of acridine of the general formula (I): wherein R¹ means A if R² means hydrogen atom, OR¹², or R² and R³ form in common double bond; R³ means hydrogen atom, or R³ and R² form in common double bond; R⁴ means CH₂NR¹⁴R¹⁵; R⁵ means hydrogen atom, C_1-6-alkyl; R⁶ means hydrogen atom, C_1-6-alkyl; R⁷ and R⁸ mean hydrogen atom; or R³ means A if R¹ means hydrogen atom or R¹ and R⁴ form in common double bond; R² means hydrogen atom; R⁴ means hydrogen atom, OR¹² or R⁴ and R¹ form in common double bond; R⁵ means hydrogen atom; R⁶ means CH₂NR¹⁴R¹⁵; R⁷ and R⁸ mean hydrogen atom; or R⁵ means A if R¹-R⁴ mean hydrogen atom; R⁶ means hydrogen atom, OR¹² or R⁶ and R⁷ form in common double bond; R⁷ means hydrogen atom or R⁷ and R⁶ form in common double bond; R⁸ means CH₂NR¹⁴R¹⁵; A represents: ; R⁹ and R¹⁰ mean hydrogen atom; R¹¹ means OH or C_1-6-alkoxy-group; R¹² means hydrogen atom; R¹⁴ and R¹⁵ mean C_1-6- alkyl; X identical with N if Y identical with C; or X identical with C if Y identical with N. Invention describes also method for preparing derivatives of acridine of the general formula (I). Invention provides preparing compounds used as analgetic agents. EFFECT: improved preparing method, valuable medicinal properties of compounds. 8 cl, 1 tbl, 11 ex