FIELD: organic chemistry, chemical technology, pharmacy. SUBSTANCE: invention describes derivatives of acridine of the general formula (I): wherein R1 means A if R2 means hydrogen atom, OR12, or R2 and R3 form in common double bond; R3 means hydrogen atom, or R3 and R2 form in common double bond; R4 means CH2NR14R15; R5 means hydrogen atom, C1-6-alkyl; R6 means hydrogen atom, C1-6-alkyl; R7 and R8 mean hydrogen atom; or R3 means A if R1 means hydrogen atom or R1 and R4 form in common double bond; R2 means hydrogen atom; R4 means hydrogen atom, OR12 or R4 and R1 form in common double bond; R5 means hydrogen atom; R6 means CH2NR14R15; R7 and R8 mean hydrogen atom; or R5 means A if R1-R4 mean hydrogen atom; R6 means hydrogen atom, OR12 or R6 and R7 form in common double bond; R7 means hydrogen atom or R7 and R6 form in common double bond; R8 means CH2NR14R15; A represents:
; R9 and R10 mean hydrogen atom; R11 means OH or C1-6-alkoxy-group; R12 means hydrogen atom; R14 and R15 mean C1-6- alkyl; X identical with N if Y identical with C; or X identical with C if Y identical with N. Invention describes also method for preparing derivatives of acridine of the general formula (I). Invention provides preparing compounds used as analgetic agents. EFFECT: improved preparing method, valuable medicinal properties of compounds. 8 cl, 1 tbl, 11 ex
Title | Year | Author | Number |
---|---|---|---|
DERIVATIVES OF HETEROCYCLIC BENZOCYCLOALKENES AND METHOD OF THEIR SYNTHESIS | 1998 |
|
RU2197484C2 |
SUBSTITUTED INDOLE MANNICH BASES | 2000 |
|
RU2265594C2 |
SUBSTITUTED AMINO-COMPOUNDS AND METHOD OF THEIR SYNTHESIS | 1998 |
|
RU2197474C2 |
DIMETHYL-(3-ARYLBUT-3-ENYL)-AMINO-COMPOUNDS AND METHODS OF THEIR SYNTHESIS | 1997 |
|
RU2167146C2 |
NEW DERIVATIVES OF PROPARGYL ETHER | 2000 |
|
RU2237058C2 |
SUBSTITUTED CYCLOHEPTENES AND METHOD FOR THEIR PREPARING | 1999 |
|
RU2233268C2 |
THIOPYRIDINES USED FOR CONTROL OF HELICOBACTER BACTERIA | 1995 |
|
RU2142459C1 |
SUBSTITUTED BICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF INHIBITION | 1998 |
|
RU2204557C2 |
FUNGICIDAL COMPOSITIONS | 2012 |
|
RU2592554C2 |
COMPOUNDS REPRESENTING STYRENE DERIVATIVES FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | 2008 |
|
RU2494089C2 |
Authors
Dates
2004-03-10—Published
1999-07-05—Filed