FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing 1,4 : 3,6- -dianhydro-D-sorbitol that is a semi-product in manufacturing medicinal preparations on the basis of its mono- or dinitro-derivatives. Method for preparing 1,4 : 3,6-dianhydro-D-sorbitol involves dehydration of 75-80% solution of sorbitol at increased temperature in the presence of acid catalyst, such as benzenesulfoacid or sulfuric acid, taken in the amount 0.65-1.0 mas.-%. Process of distillation off is carried out using capillary through that inert gas (nitrogen, carbon dioxide) is fed at the reaction mass temperature in the still above 130 C. Invention provides increasing yield and quality of the end product, reducing heat and energy consumptions. EFFECT: improved preparing method. 1 tbl, 10 ex
| Title | Year | Author | Number |
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