ORAL GALENICS WITH RAPID RELEASE AND SUSTAINED-RELEASE COMPRISING ABSORPTION-ENHANCING AGENT AND APPLICATION OF THIS ABSORPTION-ENHANCING AGENT Russian patent published in 2004 - IPC

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to galenic compositions for oral administration providing the enhanced absorption of substance that act in digestive tract by trans-membrane or para-cellular way that exhibit hydrophilic or ionizing properties in physiological media. Composition comprise at least one active substance, absorption-enhancing agent with a value of hydrophilic-lipophilic balance above 8. This absorption-enhancing agent comprises one or some lipid compounds taken among group including polysorbates, polyoxyethylene and alkyl ethers, polyoxyethylene and fatty acid esters, fatty acids, saturated alcohols, bile acid and their salts with pharmaceutically acceptable cations, -alcanol and fatty acid esters, polyol and fatty acid esters wherein polyol comprises from 2 to 6 hydroxyl functionally active group and polyglycosylated glycerides in combination with one or some pharmaceutically acceptable excipients. Invention relates to application of absorption-stimulating agent in preparing galenic compositions. Invention relates to a method for preparing galenic composition by wetting granulation of active substance and excipients and pressing being an active substance is used at the granulation stage as wetting liquid. Invention provides realization of indicated designation. EFFECT: valuable medicinal and pharmaceutical properties of galenics. 15 cl, 13 tbl, 9 dwg, 21 ex