ANESTHETIC MAINTENANCE METHOD FOR MONITORING SPINAL CORD FUNCTIONS IN PERFORMING SURGICAL OPERATION Russian patent published in 2004 - IPC

FIELD: medicine. SUBSTANCE: method involves intramuscularly administering premedication with Relanium at a dose of 0.2 mg/kg and Dimedrol at a dose of 0.4 mg/kg, introducing anesthesia with Fentanyl at a dose of 0.002 mg/kg and Prophanol at a dose of 4-5 mg/kg. Trachea intubation is done after applying Nimbex at a dose of 0.15 mg/kg. Artificial lung ventilation is carried out with an apparatus operating in in-flow mode with inhalation plateau and oxygen concentration equal to 40% in the inhaled mixture. Required monitoring includes electrocardiogram, arterial blood pressure measuring (diastolic, systolic, mean), heartbeat rate measuring, SaO₂, ETCO measurements. Anesthesia is supported with continuous Propophol infusion at a dose of 6-8 mg/kg/h within the first 30 min and then at a dose of 4-5 mg/kg/h. Myoplegia is supported by applying Nimbex at a dose of 0.1 mg/kg/h within the first 60 min and then at a dose of 0.05 mg/kg/h. Analgesia is supported by applying Fentanyl at a dose of 0.004 mg/kg within the first 60 min and then at a dose of 0.002 mg/kg. The last Fentanyl administration is carried out 30 min before awakening, Propophol and Nimbex doses are reduced to twice as low 20 min before awakening their supply is stopped 5 min before awakening. Fentanyl is administered at a bolus dose of 0.002 mg/kg, Propophol 4 mg/kg and Nimbex 0.1 mg/kg after spinal cord functions monitoring is over. Then, continuous Propophol infusion at a dose of 6-8 mg/kg/h Nimbex 0.05 mg/kg/h and Fentanyl is administered at a bolus dose of 0.002 mg/kg/h. EFFECT: enhanced effectiveness when intra-operation recovery is needed for checking neurologic disorders. 4 cl