COMPOUNDS, PHARMACEUTICAL COMPOSITION, METHOD FOR PREVENTING NERVOUS CELL DEATH, METHOD FOR PROPHYLAXIS Russian patent published in 2004 - IPC

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention relates to a new compound characterizing with the high degree of antagonism with respect to calcium, in particular, neuron-selective antagonism with respect to calcium. Invention relates to compound of the following formula, it salt or hydrate: . In indicated formula Ar means optionally substituted 5-14-membered aromatic ring and so on; ring A represents any ring taken among piperazine, homopiperazine, piperidine and similar ones; ring B represents optionally substituted (C_3-14)-hydrocarbon ring and so on; E means a simple bond, group of the formula -CO- and so on; X means a simple bond, oxygen atom and so on; R¹ means hydrogen atom, halogen atom, hydroxyl group and similar ones; D¹, D², W¹ and W² have similar or different values and each represents a simple bond or optionally substituted (C_1-6)-alkylene chain. EFFECT: improved prophylaxis method, valuable medicinal properties of compounds.