FIELD: polymer materials.
SUBSTANCE: invention is dealing with water-soluble biodegradable three-block polymer. Polymers ABA or BAB contain 51-83 wt % of polyester-based hydrophobic block A and 17-49 wt % of hydrophilic polyethylene glycol block B. Three-block polymer possesses average molecular mass 2000-4990 and reversible thermal gelling properties. Aqueous compositions containing 0.01 to 20% of medicament and 3 to 50% of biodegradable three-block polymer are used for transportation of medicament.
EFFECT: enabled thermal gelling allowing existence of polymers in the form of aqueous solution at low temperatures and reversible gelling at physiologically appropriate temperatures so ensuring good medicament release characteristics.
25 cl, 6 dwg, 3 tbl, 10 ex
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Authors
Dates
2004-07-20—Published
1999-09-30—Filed