FIELD: medicine.
SUBSTANCE: there are used biocompatible, biodegradable sustained-release implants and microspheres comprising an antihypertensive agent and a biodegradable polymer for placing inside the chamber or an anterior portion of the vitreous body. A microsphere diameter is from 30 to 100 mcm; the microspheres contain 10 to 30 wt % of the antihypertensive agent and 70 to 90 wt % of the biodegradable polymer. The antihypertensive agent is released within 10 to 120 days.
EFFECT: group of inventions enables providing the higher clinical effectiveness of the hypertensive eye condition, such as glaucoma.
12 cl, 9 ex, 10 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATING ELEVATED INTRAOCULAR PRESSURE USING INTRAOCULAR SUSTAINED RELEASE DRUG DELIVERY SYSTEM | 2014 |
|
RU2664686C2 |
| REDUCTION OF INTRAOCULAR PRESSURE BY INTRACHAMBER BIMATOPROST IMPLANTS | 2011 |
|
RU2586298C2 |
| INTRACHAMBER IMPLANTS WITH PROLONGED RELEASE OF THERAPEUTIC AGENT | 2011 |
|
RU2565445C2 |
| INTRAOCULAR IMPLANTS CONTAINING PROSTAMIDE AND METHODS OF THEIR USE | 2014 |
|
RU2650614C2 |
| INTRAOCULAR DRUG DELIVERY SYSTEMS | 2007 |
|
RU2440102C2 |
| METHOD OF TREATING ATROPHIC AGE-RELATED MACULAR DEGENERATION | 2009 |
|
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| METHOD FOR TREATING ATROPHIC AGE RELATED MACULAR DEGENERATION | 2009 |
|
RU2668371C2 |
| INTRAOCULAR IMPLANTS CONTAINING PROSTAMIDES | 2014 |
|
RU2666603C2 |
| IMPLANT FOR PROLONGED DRUG DELIVERY | 2014 |
|
RU2641021C2 |
| DEVICE FOR DELIVERY OF INTRAOCULAR IMPLANT AND METHODS OF ITS USE | 2015 |
|
RU2728195C2 |
