FIELD: medicine.
SUBSTANCE: preparation comprises compound of the formula (I): glycosyl - Y[-C(=Y)-X-]p-W(R)n-X-C(=Y) - active substance (I) wherein radical values, p and n are given in the invention claim, sugar and/or sugar alcohol, pharmaceutically acceptable carrier and, optionally, bivalent ions of metals: Ca, Mg, Fe, Cu or Ni. The preferable compound of the formula (I) is doxorubicin. The preparation is used in treatment of malignant tumors, inflammatory processes and autoimmune diseases. Modifying the preparation provides the improved tolerance in vivo and enhanced effectiveness of action.
EFFECT: improved and valuable medicinal properties of preparation.
7 cl, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| LOW-MOLECULAR CONJUGATES OF ANTITUMOUR AGENTS AND HIGHLY SELECTIVE LIGANDS OF ASIALOGLYCOPROTEIN RECEPTOR FOR THERAPY OF ONCOLOGICAL LIVER PATHOLOGIES | 2017 |
|
RU2696096C2 |
| NOVEL PENTASACCHARIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF | 1999 |
|
RU2193040C2 |
| PRODRUG FOR THERAPY OF TUMORS AND INFLAMMATORY DISEASES | 1997 |
|
RU2191021C2 |
| POLYMER CONTAINING MEDICINAL AGENT BASED ON ANTITUMOR AGENT ETOPOSIDE | 2015 |
|
RU2595859C1 |
| ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY | 2009 |
|
RU2531591C2 |
| METHODS FOR TREATING PANCREATIC CANCER | 2017 |
|
RU2768479C2 |
| GLYCOLIPID COMPOUNDS AND USE THEREOF IN TREATING TUMOURS | 2015 |
|
RU2719486C2 |
| CONJUGATES OF DISORAZOL, BASED PHARMACEUTICAL COMPOSITIONS, SAID CONJUGATES FOR PREPARING DRUG, KIT AND METHOD FOR PREPARING THEM | 2007 |
|
RU2473562C2 |
| METHOD OF TREATMENT BY APPLICATION OF COMBINED THERAPY | 2010 |
|
RU2543348C2 |
| COMBINATION THERAPY WITH ANTICANCER ALKALOID | 2018 |
|
RU2767664C2 |
