ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY Russian patent published in 2014 - IPC C07K7/08 C07K14/81 A61K47/48 A61K31/337 A61K31/706 A61P35/00 

Abstract RU 2531591 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to polypeptides having hydrolysable covalent bonds with therapeutic agents for drug delivery. The invention also refers to pharmaceutical compositions which contain the compounds according to the invention, to using them in methods of treating cancer.

EFFECT: polypeptide conjugates can be used as vectors for a therapeutic agent transport through the blood-brain barrier (BBB) and for delivery into specific types of cells, such as the ovaries, liver, lungs or kidneys.

6 cl, 16 dwg, 8 tbl, 6 ex

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RU 2 531 591 C2

Authors

Demole Mishel'

Che Kristian

Gabatuler Rajnkhard

Jang Gaotsjan

Dates

2014-10-20Published

2009-10-15Filed