FIELD: organic chemistry, amino acids, pharmacy.
SUBSTANCE: invention relates to derivatives of β-alanine of the general formula (I):
wherein Q1 or Q3 mean CH or nitrogen atom (N) independently of one another but they can't mean simultaneously nitrogen atom (N); R1 represents hydrogen atom (H), A, Ar or Hal; R2 means hydrogen atom (H) or A; R3 means
,
or
;
each among R4 and R5 means independently hydrogen atom (H), A or Hal; R6 represents hydrogen atom (H) or A; A represents alkyl with 1-6 carbon atoms; Ar represents unsubstituted aryl; Hal means fluorine (F), chlorine (Cl), bromine (Br) or iodine (J) atom; n = 2, 3, 4, 5 or 6; m = 1, 2, 3 or 4, and to their physiologically acceptable salts or solvates also, and to methods for their preparing and to a pharmaceutical preparation eliciting property of inhibitor of integrins.
EFFECT: improved preparing method, valuable biological and medicinal properties of compounds.
7 cl, 27 ex
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