FIELD: medicine; pharmacology.
SUBSTANCE: compounds of this invention possess properties of protein kinase inhibitors. In the general formula 
p means integer within 0 to 2; R and R1 mean O; A1 and A2 mean single bond, (C1-C6)alkyl; B2 means monocyclic or bicyclic, saturated or unsaturated heterocyclic radical including 1 to several identical or different heteroatoms, chosen among O, S, N and NR7, probably substituted with one or several identical or different substitutes.
EFFECT: inhibiting effect on protein kinase, effective application of compounds of formula for medical products.
49 cl, 1 tbl, 6 dwg, 334 ex
| Title | Year | Author | Number |
|---|---|---|---|
| IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, POSSESSING ANTIPROLIFERATIVE ACTIVITY | 2010 |
|
RU2555999C2 |
| IMIDAZOLONE AND IMIDAZOLIDINONE DERIVATIVES AS 11B-HSD1 INHIBITORS FOR DIABETES | 2007 |
|
RU2439062C2 |
| HYDANTOIN DERIVATIVE | 2013 |
|
RU2678984C2 |
| NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | 2021 |
|
RU2814288C1 |
| CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DESTRUCTION OF ANDROGEN RECEPTORS AND USE THEREOF | 2020 |
|
RU2825000C2 |
| DERIVATIVES OF HYDRAZONE-PYRAOLE AND MEDICAL APPLICATION THEIROF | 2002 |
|
RU2332996C2 |
| NOVEL DUAL ACTING ATI AND ETA RECEPTOR ANTAGONISTS (DARA) | 2007 |
|
RU2425833C2 |
| BIPHENYLMETHYLTHIAZOLIDINEDIONS AND ANALOGUES AND THEIR USING AS PPAR-GAMMA ACTIVATORS | 2002 |
|
RU2323212C2 |
| NOVEL IMIDAZOLIDINE-2,4-DIONE DERIVATIVES | 2013 |
|
RU2650678C2 |
| METHOD FOR PREPARING AMMONIUM SALTS OF 3-AMINO-8-HYDROXY-1,6-DIOXO-4-CYANO-2,7-DIAASPIRO [4,4] NON-3-EN-2-IDS | 2016 |
|
RU2631856C1 |
