INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING ALPHA-V-BETA-3 Russian patent published in 2017 - IPC C07D207/452 C07D239/14 C07D277/593 C07D417/12 A61K47/50 A61K47/60 A61P35/00 

Abstract RU 2623441 C2

FIELD: chemistry.

SUBSTANCE: invention relates to compounds of formula for application in the manufacture and delivery of conjugated molecules, such as low molecular compounds, peptides, nucleic acids, fluorescent molecules and polymers, which are connected with the integrin antagonists of alpha-V-beta-3, to target the cells expressing alpha-V-beta-3.

EFFECT: improved properties.

17 cl, 10 dwg, 1 tbl, 14 ex

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RU 2 623 441 C2

Authors

Gudnau Dzh. Robert Alan

Gamilton Metyu Majkl

Kovalchik Agneshka

Sidduri Achyutarao

Dates

2017-06-26Published

2013-01-22Filed